IgAnephropathy

Symptoms: gross hematuria or proteinuria, youngsters are likely to suffer this disease, especially for male. Mucous membrane lesion is commonly seen in the early stages, 24-72 hours after infection, the majority of patients will show gross hematuria.

Conventional therapy: the common treatment is to use hormone or immunosuppressor to simply restain protein in urine while ignore the causes of the disease----repair kidney epithelial cell. Long-term oral intake of traditional Chinese medicine could bring about huge side effects to patients, such as nausea, vomiting and other gastrointestinal problems.

The advantage of our treatment: we treat the disease from the cause of hematuresis, lay stress on repairing mesangial cell. The treatment we offer to patients is a integrated therapy which combines both traditional Chinese medicine and western medicine while the primary treatment is still traditional Chinese medicine through measures of vascular dilation, anti-inflammatory, anticoagulation and degradation of hazardous substance. We promise if the damaged intercapillary cells be repaired, patients’ condition will be improved and the red blood cell in urine will disappear naturally.

nephritis

Symptoms: most of patients have different level swelling and high blood pressure, severe swelling will appear urine volume reduce, even night urine volume increase. Most of patients will appear different conten proteinuria, the night urine volume will increase while the kidney be damaged, urine specific gravity reduce, urinary sediment test abnormal.

Conventional therapy: hormone immunosuppressant therapy, diuretic therapy, treatment and anticoagulant therapy, the main is repair the damaged resident cells

The advantage of our treatment: repair damaged resident cells, blocking-up fibrosis, completely repair cells and the symptoms will be gone.

nephrotic syndrome

Symptoms: the main clinical manifestation is severe swelling, hyperlipemia, large number of proteinuria, hypoproteinemia.

Conventional therapy: hormone immunosuppressant therapy, anticoagulant therapy, lipid-lowering, calcium supplement, diuresis detumescence treatment.western medicine can’t completely repair kidney resident cells, it just alleviate protein spilling, if patients not sensitive to hormone, the curative effect is unsatisfactory, it not deal with the cause of disease, but alleviate the symptoms.

The advantage of our treatment: completely repair damaged resident cells, vascular dilation, improve the condition of glomerulus ischemia and hypoxia,blocking-up kidney fibrosis.

PKD( polycystic kidney disease)

Symptoms: most of patients have family history, man is more than woman, the common symptoms are waist and abdominal pain(initial symptom for most of patients, persistent or paroxysmal, after overwork will be serious), hematuresis( initial symptom, about half patients will appear), stomach goitre.

Conventional therapy: operative treatment, such as cut cyst and decompression operation, the operation can alleviate the pressure of cyst to kidey and help kidney repair in short term, however, there is a chance for samll cysts to grow up, and the patients disease will replase.

The advantage of our treatment:it aim at restrain the trend of cyst growing, reduce the source of cyst fluid, inactivation epithelial cell of cyst, restain cyst fluid secretion and stop cyst grow up, increase the cyst fluid excretion, increase blood circulation and permeability of cyst surface, then, make cyst retraction.

Kidney cyst

Symptoms: in generally, no symptoms, most of patients be detected by physical examination or due to other disease to have imageological examination. Part of patients feel damaged kidney side back pain, but it often not direct caused by kidney cyst. Big cyst, especially the cyst that internal haemorrhage or infection will appear obvious back pain. For example, if cyst happen press ureter or the neck of kidney calices will cause hydronephrosis and secondary infection, then, patients will appear back pain, fever, urinary tract infection and other symptoms.

Conventional therapy: operative treatment( renal biopsy),expectant treatment

The advantage of our treatment:it aim at restrain the trend of cyst growing, reduce the source of cyst fluid, inactivation epithelial cell of cyst, restain cyst fluid secretion and stop cyst grow up, increase the cyst fluid excretion, increase blood circulation and permeability of cyst surface, then, make cyst retraction.

Renal insufficiency

Symptoms: patients in compensated stage or decompensated period may have no symptom, sometimes, patients will only suffer weakness, back pain, increased urine volume and other symptoms, a small number of patients will suffer anorexia,metabolic acidosis and mild anemia. When the condition develops into middle stage of renal insufficiency, the symptoms will be more obvious and more serious. Acute heart failure, severe hyperkalemia,alimentary tract hemorrhage, central nervous system disorder, swelling and other life-threatening symptoms may appear once the patient’s condition develops into end stage renal disease which is also known as uremia.

Conventional treatment option: dialysis, kidney transplantation. Dialysis only can alleviate poison damage to human body in short-term, but cpmpletely treat kidney disease; kidney transplant has high risk and need zygosity, the cost is high, after patients have kidney transplant need take anti-rejection drugs all the time.

The advantage of our treatment: completely repair damaged resident cells, improve kidney function, enhance glomerular filtration rate

Kidney failure

Symptoms:

1.digestive system: stomatitis, gastritis,colitis, loss of appetite, nausea, vomiting, diarrhea, mouth smell like urine, etc

2.cardiovascular system: high blood pressure, arrhythmia, heart failure, pericarditis, part of patients may appear hydropericardium.

3.respiratory system: patients breath has ammoniacal odour, the breath fast and deep, patients will appear end stage kidney failure,

uremia pneumonia while condition worse.

4.hemopoietic system: the common symptoms is anemia and bleeding tendency

5.nervous system: patients easy weak, hypomnesis, dysphoria, insomnia, at the end stage, patients will appear lethargy, delirious speech, coma , mania and so on.

6.skin and mucosa: such as pigmentation, skin pruritus, etc

7.water, electrolyte, acid-base disturbance disorder: when kidney concentrating function reduce, may appear enuresis nocturna increase or glomerular filtration rate decline and cause urine volume reduce. When patients enter into end stage may appear increased blood phosphorus, decline blood calcium and the symptoms of high phosphorus.

Conventional therapy: substitution therapy, it include gastro-intestinal dialysis ,colon dialysis , peritoneal dialysis, skin dialysis and so on. Dialysis can alleviate toxin damage human body in short-term, but completely treat kidney disease, kidney transplant has high risk and need zygosity, the cost is high, after patients have kidney transplant need take anti-rejection drugs all the time. Take anti-rejection drugs for a long time can cause gastrointestinal symptom, such as nausea, vomiting and so on.

The advantage of our treatment: although patients with kidney failure large area renal unit has been damaged, however, there are still a part of the cell can work normally, thus, the key of treatment is repair damaged kidney unit, protect epibiotic kidney function, blocking-up kidney induration and fibrosis, avoid development to uremia, finally, get rid of dialysis and kidney transplant.

uremia

Symptoms:

1.swelling: due to kidney can’t remove redundant water in human body and lead to liquid retention in Interstitial space of body. In early stage, patients only ankle and eyelid swelling, after have a rest will disappear, if patients swelling develpment to persistence or the whole body swelling, that’s mean the disease is very serious.

2.urine volume change: due to kidney function reduce, part of patients as disease development urine volume will reduce gradually. Due to reduce discharge the toxin in urine, quality decline and can’t discharge too much waste of body, in addition, urine volume can’t completely stand for whether kidney function good.

3.sleeply, weak; those symptoms are easy be ignored.

4.high blood pressure: due to kidney has the function of discharge of sodium and water, after kidney be damaged, sodium and water will retention in body. At that time, kidney also secretion some substance, which will rise high blood pressure, thus, patients with kidney disease appear different level high blood pressure in early stage. If high blood pressure and poor clotting mechanism are easy lead to nose or teeth bleeding, patients should pay attention to it.

5.poor appetite: it caused by urotoxin retention and influence digestive function, as disease development, patients will appear abdominal discomfort,nausea, vomiting,even Defecate frequency or defecate completely mashed, at this time, the disease is severe, the common symptoms of end stage kidney failure and early stage uremia is nausea, vomiting, loss of appetite and other digestive tract symptoms.

6.face yellowing

Conventional therapy: dialysis, kidney transplant and traditional Chinese medicine treatment. Dialysis only can alleviate poison damage to human body in short-term, but cpmpletely treat kidney disease; kidney transplant has high risk and need zygosity, the cost is high, after patients have kidney transplant need take anti-rejection drugs all the time.Take anti-rejection drugs for a long time can cause gastrointestinal symptom, such as nausea, vomiting and so on.

The advantage of our treatment: blood stasis therapy original creation treat disease from multi-angle,multi target point, multi-stage, multi methods completely, the treatment as traditional Chinese medicne be major treatment,give full play to the characteristics of traditional Chinese medicine, such as richness,uniqueness,small side effects and so on,meanwhile, combine the new methods and new means of modern science and technology, it is the perfect combination of Chinese medicine and western medicine, traditional and modern. Take many measure and aim at it, let more and more patients with kidney disease get rid of dialysis as soon as possible.

Secondary nephropathy

hypertensive nephropathy:(High blood pressure type of ischemic disease of glomerular endothelial cells)

Symptoms: blood pressure more than 140/90, swelling, protein spilling, nocturia increased.

Conventional therapy: lowering blood pressure and take some only eliminate proteinuria medicine, it only symptomatic treatment, but aim at the cause of kidney disease that glomerular endothelial cell be damaged to treat.

The advantage of our treatment: aim at the cause of proteinuria to treat, that’s mean lay stress on repair endothelial cells, the measures of treatment is comprehensive take vascular dilation, anti-inflammatory, anti-freezing,degradation hazardous substance and other measures.

Diabetic Nephropathy

Symptoms:For the normal person ,the fasting blood glucose is 80 ~ 120 mg % in the morning. Fasting plasma glucose more than 130 mg % called high blood sugar.

Early symptoms of the high blood suger: renal glomerular filtration rate increased to 123.8 ml/min / 1.73 / M2, microalbuminuria, urinary protein output in 20-200 mu g / / min (30-300 mg / / 24 h), this is the main characteristic of early diabetic nephropathy.

When urine albumin output amount is more than 200 mu g / / min, the total protein urine discharge is about 0.5 g / 24 h, now the symptoms known as clinical diabetic nephropathy. Late-stage of the kidney disease, the rate of glomerular filtration declined, kidney function is damaged,and appear the symptom such as creatinine increased.

General treatment: lower the blood sugar, control blood pressure, limit proteinuria with drugs, control diet, dialysis in the late-stage,and transplant kidney in the end.

Our hospital treatment advantage: our hospital treat the kidney disease from the underlying .that is mean focus the treatment on the endothelial cells, epithelial cells and mesangial cells,to repaire these cells.

Treatment measures is expansion blood vessel, anti-inflammatory, anticoagulation and take measures to degradation the harmful substances.

Lupus nephropathy (lupus glomerular capillary epithelial cell disease)

Symptoms: lupus belong to the autoimmune diseases, hematuria and proteinuria patients with no edema and high blood pressure,just have the mild or moderate proteinuria and hematuria.

Nephritis syndrome is often associated with edema or high blood pressure, albuminuria and hematuria. Acute onset clinical manifestations are similar with the acute nephritis.,also can be associated with renal impairment. Some cases with a sudden onset, renal function deterioration sharply, progression into kidney failure in the short time, in clinical show the urgent nephritis, if no effective treatment, fatality rate is extremely high.

Conventional treatment : for mild systemic lupus erythematosus (such as only a skin rash, low thermal or joint symptoms, etc.) and 　　immunoserology test is abnormal, if the urine test is normal,kidney biopsy the serologic testing if urine, renal biopsy showed glomerulus normal or slight pathological changes,then use non-steroidal anti-inflammatory drugs to improve symptoms. Generally,the glucocorticoid or cytotoxic drugs are not needed , but need to track condition closely.

If the urine are abnormal,kidney biopsy show glomerular segmental mesangial proliferation accompanied with segmental necrosis, crescentformation,and focal segmental glomerulosclerosis.Using the small or medium dose of corticosteroids (such as prednisone 20 to 40 mg/d),according the condition add the cytotoxic drugs and tripterygium wilfordii.

For the treatment of lupus kidney, mainly use the western medicine immune inhibitors, cytotoxic drugs, such as cyclophosphamide.

Advantage of the treatment in our hospital: Immune therapy, to repair the damaged renal intrinsic cells , expanding blood vessels, such as anti-inflammatory, anticoagulation, degradation treatment.

Expansion of blood vessels: the purpose of expanding blood vessels is to try to improve the blood circulation in kidney and change the status of each system, relieve ischemia oxygen deficit of the renal inherent cells, provide a good environment for repair epithelial cells and mesangial cells.

Anti-inflammatory, purpose is to reduce inflammation cells infiltration, reduce glomerular epithelial cell injury again.

Anticoagulation: mainly to alleviate the pressure of the thrombosis,to lay a foundation for repair the epithelial cells .

Degradation: mainly to remove immune complex and extracellular matrix,and let them in vitro through urine .

Purpura nephropathy (glomerular capillary mesangial cell disease)

Symptoms: clinical symptoms include skin purpura, joint swelling pain, abdominal pain, hematochezia, mainly for hematuria and proteinuria, mostly appear in a month after skin purpura. some can see the skin purpura, abdominal pain a same time, some cases is urinary anomalies with no any other symptoms.

Conventional treatment: pay attention to rest and maintain water and electrolyte balance. Edema and with heavy proteinuria patients should be low salt, limit water and avoid eating high protein food. According to the patient's different condition , choose tripterygium wilfordii glycoside, Hormone combined cyclophosphamide, Joint ring spore, A,or tacrolimus. Mainly treatment is use the drugs.

Advantage treatment in our hospital: control drugs targets, at the same time to repair the damaged renal intrinsic cells, degradation and removal the large number of immune complex ,which are deposit on the kidney inherent cells.

High uric acid nephropathy (gouty nephropathy) : (high uric acid type of renal tubular epithelial cell disease)

Symptoms: mostly appear in middle-aged and old male, female are rare, with gouty arthritis and gout, mild proteinuria, quantitative is generally not more than 1.5 grams every 24 hours, the patient often merge mild-to-moderate hypertension, hyperlipemia, metabolic syndrome, easy to produce the renal atherosclerosis and cardiovascular disease.

Conventional treatment : hormone and cytotoxic drugs to anti-inflammatory, eating the promoting uric acid excretion drugs, diet restriction or prohibition wine and reduce the intake of purines foods .

Treatment in our hospital: in the control of high uric acid at the same time, to repair the damaged renal intrinsic cells to expand blood vessels, anti-inflammatory, anticoagulation, and degrading treatment.

Hepatitis b associated nephropathy (hepatitis b type glomerular capillary epithelial cell disease)

Symptoms: hepatitis b surface antigen, hepatitis b e antigen or antibody of second liver core continuous positive or hepatitis b DNA many times show positive, with or without transaminase increased, such as hematuria, edema, hypertension, glomerulonephritis performance or for nephrotic syndrome.

Conventional treatment methods: mainly use the immunosuppressants and hormonal drugs.

Our hospital treatment advantage: not only just treat the protein and occult blood ,we are focusing on to erpaire the damaged renal intrinsic cells, degradation and removal a large number of immune complex,which deposit on the kidney inherent cells.

Diagnose the disease type after the kidney biopsy

Mesangial proliferative glomerulonephritis:

Under the light microscope show glomerulonephritis with glomerular diffuse mesangial cell proliferation and /or mesangial matrix increased

Symptoms: MsPGN visible at all ages, but teenagers more, men more than women, men and women by a ratio of about 1.5 to 2.3:1. Most patients show hidden onset. About 30% ~ 40% were infected before the onset , usually is upper respiratory tract infection. Have a history of precursor infection may appear acute episode. Asymptomatic proteinuria and/or blood in the urine , nephrotic syndrome or nephritis syndrome. This disease with a high incidence of blood in the urine, about 70% ~ 90% of cases with hematuria, often as microscopic haematuria, 20% ~ 30% can be characterized by recurrent episodes of naked eye hematuria. Albuminuria is different, but usually as a non-selective proteinuria.

Conventional treatment : hormones or immunosuppressive therapy treatment.

Treatment in our hospital: immune therapy+Repair + degradation.

Membrane proliferative kidney disease:

Also called mesangial capillaries glomerulonephritis, can occur in children and adults, the main pathological changes is mesangial cell proliferation , mesangial matrix increase and irregular thickening of glomerular basement membranes.

Symptoms: In early-stage symptoms is not obvious, show different clinical symptoms, often with proteinuria, blood in urine. About half of the patients manifestation nephrotic syndrome, and often have high blood pressure and renal insufficiency. In the late-stage, the entire glomerular sclerosis, disease duration long time, hormone therapy have no obvious effect, easy to develop into kidney failure. Some patients serum complement is reduced, so also called as low complement glomerulonephritis.

Conventional treatment methods: hormones or immunosuppressive therapy treatment.

The advantage of treatment in our hospital: immune therapy. Repair + blocking-up + degradation.

Membranous nephropathy:

Pathology changes refers to a large quantity of the immune complex deposits glomerular capillary loop epithelial side. Mostly are the over 40 years old patients, most of the patients with nephrotic syndrome as a onset disease, about 20% patients are asymptomatic, proteinuria is non nephrotic range.

Symptoms: Mostly are the over 40 years old patients, male to female ratio is about 2:1. most of the patients with nephrotic syndrome as a onset disease, about 20% patients are asymptomatic, proteinuria is non nephrotic range. Membranous nephropathy patients proteinurine quantitative are rarely more than 15 g/d. About half of the patients with microscopic haematuria.

Conventional treatment methods: hormones or immunosuppressive therapy treatment. The advantage of treatment in our hospital: immune therapy. Repair + blocking-up+ degradation. + degradation.

Minimal change disease,MCD

By the light microscope , found that the renal corpuscle has no obvious lesion, proximal renal tubular epithelial cells can be found the fatty degeneration. Immunofluorescence is negative. Under the electron microscope can be found renal corpuscle sertoli cell have foot process fusion. On clinical mainly show nephrotic syndrome, there is a lot of proteinuria, hypoalbuminemia, edema, hyperlipidemia, etc. MCD onset mainly in children and adolescents, often occurs in children under the age of 10, the peak at the age of 2 to 4.

The purpose of this treatment is to reduce drugs’ adverse reactions as soon as possible,that’s main use the righr dose drugs which can bring the least adverse reactions,try best to keep patients’remission in a long time.

Conventional treatment methods: hormones or immunosuppressive therapy treatment.

The advantage of treatment in our hospital: immune therapy. Repair + blocking-up + degradation.

Focal segmental glomerular sclerosis,FSGS:

Adults and children nephrotic syndrome (NS) usually will appear primary glomerular disease. The histopathological features is glomerular segmental scar, with or without foam cell formation and adhesion in glomerular capillary.

Symptoms: tend to occur in children and adolescents, men more than women slightly. A few patients before the onset suffered upper respiratory tract infection or allergic reaction. About two-thirds of the patients with large quantity of proteinuria and severe edema, urine protein quantity can be in 1 ~ 30 g/d, about more than 50% of the patients with hematuria, microscopic haematuria, accidentally see naked eye hematuria. About 30% ~ 50% of adults patients with mild persistent hypertension or characterized by chronic nephritis syndrome, patients 24 h urine protein < 3.5 g/d, edema is not obvious, often have blood in urine, hypertension and renal insufficiency.

Conventional treatment methods: hormones or immunosuppressive therapy treatment.

The advantage of treatment in our hospital: immune therapy. Repair + blocking-up + degradation.